A 14-year-old boy was referred because of a slight swelling of the alveolar mucosa of the right central and lateral maxillary incisor. Radiographically, a well-circumscribed radiolucency was seen between the vital, but partially resorbed roots of the two incisors. Treatment consisted of careful enucleation, including removal of the two teeth. Histopathological examination showed a central giant-cell granuloma. Healing was uneventful. Additional examination for the presence of hyperparathyroidism was negative. During one year follow-up, no signs of recurrence have been noticed.