Dutch adolescents attitudes towards orthodontic treatment and the determinants of these attitudes are unknown. The aim of the present study was to evaluate treated and untreated adolescents attitudes towards orthodontic treatment, and to examine possible determinants of these attitudes. Previously treated adolescents were found to have a more positive attitude towards orthodontic treatment than untreated adolescents. Age, but not gender, was found to be a significant predictor for their general attitude towards orthodontic treatment. Consequently, it was concluded that attitudes were not determined by one specific aspect, but by a combination of several determinants.